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Adenosine A2A Receptor Functional HEK293 Cell Line詳細(xì)信息
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Description
Adenosine A2A receptor (A2aR or ADORA2A) stably expressed in HEK293 cells (NM_000675.5). A2aR is a member of the seven transmembrane G protein-coupled receptor (GPCR) family. The activity of A2aR is mediated by Gαs protein which activates adenylyl cyclase, resulting in the synthesis of intracellular cAMP. The level of cAMP correlates with the level of adenosine. This cell line can be used to measure the EC50 and IC50 values of A2aR agonists or antagonists.
Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.
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Synonyms
Adenosine receptor A2a, ADORA2A, ADORA2
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Product Data Gallery
Expression of human A2aR on HEK293 cell surface
Agonist-induced cAMP (fold induction) in A2aR HEK293 cells
Antagonist dose response in A2aR HEK293 cells
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